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Withdrawal of antihypertensive medication: A systematic review

Journal of Hypertension Evidence based | Sep 02, 2017

van der Wardt V, et al. – This study investigated the proportion of people remaining normotensive for 6 months or longer following cessation of antihypertensive therapy and, the safety of withdrawal. As per data, a successful withdrawal was predicted by monotherapy, lower blood pressure before withdrawal and body weight. Minor adverse events were commonly reported after withdrawal, such as, headache, joint pain, palpitations, oedema and a general feeling of being unwell. Prescribers should consider offering patients with well controlled hypertension a trial of withdrawal of antihypertensive treatment with subsequent regular blood pressure monitoring.
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