Lorem GF, et al. - Utilizing a cohort study design combining a survey approach with repeated physical examinations, the independent effects of BMI on mortality and self-reported health (SRH) were reported. Authors, in addition, assessed whether these independent effects change as people grow older. They recognized that BMI affected SRH and all-cause mortality irrespective of comorbidity, mental health, health-related behaviors and other biological risk factors. Being underweight seemed correlated with excess mortality as compared to all others, and age affected the thinnest subjects more than all others. Weight gain seemed beneficial regarding mortality but not regarding SRH among the underweight. There appeared a rapid decline of SRH with increasing age, suggesting paying particular attention to underweight after 38 years of age.