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Vitamin D status is associated with muscular strength in a nationally representative sample of US youth

Acta Pediatrica Apr 02, 2020

Laurson KR, et al. - In a nationally representative sample of US youth, researchers explored the connection between serum 25‐hydroxyvitamin D (25OHD) and muscular strength. Participants (n = 3,350) in the study were 6‐ to 18‐y‐olds from 2011 to 2014 National Health and Nutrition Examination Survey. Using age‐ and sex‐specific z‐scores, relative handgrip strength was quantified. In order to compare strength and poor strength, defined as those <25th percentile, status by clinically relevant groupings of 25OHD, multivariate general linear and logistic models were used. Findings revealed that nearly 20.2% of youth had 25OHD < 50 nmol/L. Higher circulating vitamin D levels were linked to higher relative strength and poor strength was more prevalent when 25OHD was < 75 nmol/L. Such results illustrate the importance of vitamin D for the muscle‐bone unit and potential extraskeletal ramifications.

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