Heidary G, Fisher MJ, Liu GT, et al. - Researchers conducted a retrospective, international, multicenter study to examine the impacts of neurofibromatosis type 1-associated optic pathway gliomas (NF1-OPGs) on visual field (VF) function in a large cohort of children after treatment with chemotherapy. In total, 25 candidates underwent VF testing using formal perimetric techniques. Posterior tumor location involving the optic tracts and radiations was linked to more frequent and more profound VF defects. Findings suggested that children undergoing initial chemotherapy for NF1-OPGs had a high prevalence of VF loss, which might be independent of visual acuity loss. A larger, prospective study is required to fully evaluate the prevalence of VF loss and the effects of chemotherapy on VF outcomes in children with NF1-OPGs.