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Venous thromboembolic events in African American lupus patients are less likely associated with antiphospholipid antibodies compared to Caucasians

Arthritis Care & Research Nov 25, 2020

Gkrouzman E, Peng M, Davis‐Porada J, et al. - The present study was conducted to evaluate variations in antiphospholipid antibodies (aPL) prevalence in Caucasian and African American (AA) patients with SLE and venous thromboembolic (VTE) events, and compared inflammatory markers at the time of VTE event. In this study, 97 individuals fulfilled ACR and/or 2012 SLICC classification criteria for SLE, had a history of VTE, and available aPL tests (59 Caucasian and 38 AA). The results of this study indicated that AAs were less likely to have a clinically significant aPL profile among patients with SLE and VTE events compared to Caucasians demonstrating that a negative aPL profile in AA does not decrease VTE risk.

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