• Profile
Close

Ustekinumab for the treatment of moderate‐to‐severe plaque psoriasis in pediatric patients (≥ 6 to < 12 years of age): Efficacy, safety, pharmacokinetic, and biomarker results from the open‐label CADMUS Jr study

British Journal of Dermatology May 07, 2020

Philipp S, Menter A, Nikkels AF, et al. - Researchers conducted this phase 3, open‐label, single‐arm, multicenter study to assess the safety and effectiveness of ustekinumab in pediatric psoriasis patients (≥ 6 to < 12 years of age). For this investigation, individuals received weight‐based dosing of ustekinumab (< 60 kg: 0.75 mg/kg; ≥ 60 to ≤ 100 kg: 45 mg; >100 kg: 90 mg) administered by subcutaneous injection at weeks 0/4, then every‐12‐weeks through week 40. In total, 44 individuals (median age, 9.5 years) received at least one dose of ustekinumab. Data reported that the incidence of anti‐drug antibodies was 9.5%. In pediatric patients, ustekinumab effectively treated moderate‐to‐severe psoriasis, and no new safety concerns have been reported.

Go to Original
Only Doctors with an M3 India account can read this article. Sign up for free or login with your existing account.
4 reasons why Doctors love M3 India
  • Exclusive Write-ups & Webinars by KOLs

  • Nonloggedininfinity icon
    Daily Quiz by specialty
  • Nonloggedinlock icon
    Paid Market Research Surveys
  • Case discussions, News & Journals' summaries
Sign-up / Log In
x
M3 app logo
Choose easy access to M3 India from your mobile!


M3 instruc arrow
Add M3 India to your Home screen
Tap  Chrome menu  and select "Add to Home screen" to pin the M3 India App to your Home screen
Okay