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Usefulness of malignancy as a predictor of worse in-hospital outcomes in patients with Takotsubo cardiomyopathy

The American Journal of Cardiology Jan 04, 2019

Zaghlol R, et al. - In this retrospective chart review, researchers compared presenting symptoms, cardiac imaging and short-term events, including in-hospital complications and mortality, between two groups of hospitalized patients with diagnosis of Takotsubo cardiomyopathy (TC) between January 2006 and January 2017: those with a previous history of malignancy vs those without. A total of 81 (25.4%) out of 318 patients with TC had a previous diagnosis of cancer. The mean age of the study population was 67.5 years, 151 (47.5%) were African-American, 122 (38.4%) Caucasian, and 10 (3.1%) of other ethnicities. A higher heart rate on presentation, a higher prevalence of severely decreased cardiac function (left ventricular ejection fraction <25%), longer hospitalization, and more in-hospital cardiac arrests were seen in patients with a history of malignancy. Findings revealed a high prevalence of cancer history, which was related to adverse in-hospital outcomes.

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