Usefulness of cardiac magnetic resonance for recurrent pericarditis
The American Journal of Cardiology Nov 16, 2019
Imazio M, Pivetta E, Restrepo SP, et al. - Researchers analyzed consecutive patients (n = 128, 60 males, 47%; mean age 48 ± 14 years) with recurrent pericarditis assessed by cardiac magnetic resonance (CMR) in this multicenter cohort study in order to determine the diagnostic accuracy of CMR findings as well as their potential prognostic significance for the diagnosis of recurrent pericarditis. At a mean time of 12 days (95% confidence interval 15 to 21) following the clinical diagnosis, they performed CMR. For pericardial thickening, pericardial edema, pericardial late gadolinium enhancement (LGE), and for pericardial effusion, the respective areas under the receiver operating characteristic curve were estimated to be 64%, 84%, 82%, and 71%. The recurrences were suffered by 52% of patients (tamponade in 6%, and constrictive pericarditis in 11%) following a mean follow-up of 34 months. The use of a multivariable Cox model revealed predictors of adverse events: elevation of CRP and presence of CMR pericardial thickening, as well as lower risk in relation to the presence of CMR LGE. A C-index of 0.84 was displayed by the prognostic model for adverse events utilizing gender, age, CRP level, and all CMR variables. Overall, findings revealed a high diagnostic accuracy of CMR findings, and these may assist in the detection of cases that carry a higher risk of complications.
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