Lam AKN, To E, Weinreb RN, et al. - Researchers conducted this cross-sectional study to examine the application of virtual reality (VR) to identify vision-related disability in patients with glaucoma. Ninety-eight Chinese patients with glaucoma [mean (SD) age was 49.8 (11.6) years] and 50 healthy Chinese individuals [mean (SD) age was 48.3 (14.8) years] were consecutively recruited from a university eye clinic. Findings suggested an association of vision-related disability with task and lighting condition in patients with glaucoma, with 8.0% to 30.7% having vision-related disability in supermarket shopping, stair navigation, or city navigation. A higher proportion of patients had nighttime vision-related disabilities than daytime navigation. Such findings appear to support the idea that simulation of VR improves the evaluation of visual disability in clinical care by presenting clinicians with a new insight to consider how visual impairment imparts vision-related loss in glaucoma patients.