Tsai CM, Tang KS, Cheng MC, et al. - Given that serum C‐reactive protein (CRP) is a sensitive biomarker for inflammation and is broadly used to clinically diagnose infectious diseases, including pneumonia, however, blood sampling is fraught with technical difficulties in children, researchers conducted this prospective study to assess the use of salivary CRP as a biomarker for children with pneumonia. This investigation was carried out in patients aged 2 to 17 years, admitted to the hospital with pneumonia. The sample consisted of 60 healthy children and 106 pediatric patients with pneumonia. Both salivary and serum CRP levels decreased during follow‐up as pneumonia improved. Findings suggested that salivary CRP can be an alternative biomarker for serum CRP in pediatric pneumonia patients. This is particularly beneficial for pediatric patients since the collection of saliva is simple, non-invasive, and patient-friendly.