Chambers LM, Morton M, Lampert E, et al. - Researchers examined the influence of providing closed incision negative pressure therapy on surgical site infections in gynecologic oncology patients undergoing laparotomy compared with standard dressings. In this retrospective case-control study of patients undergoing laparotomy for known or suspected gynecologic cancer, patients were matched in a 1:3 ratio (closed incision negative pressure therapy to standard dressing) by BMI, age, diabetes, bowel surgery, smoking, and steroid use. Among 1,223 eligible patients undergoing laparotomy, 64 (5.2%) received closed incision negative pressure therapy dressings and were matched to 192 (15.7%) controls. Outcomes revealed reduced superficial incisional and deep incisional infections in gynecologic oncology patients in correlation with receiving prophylactic closed incision negative pressure therapy vs standard dressings after laparotomy. In addition, they observed reduction in all other adverse wound outcomes in correlation with closed incision negative pressure therapy. They support considering closed incision negative pressure therapy for surgical site infection prevention in high-risk gynecologic oncology patients undergoing laparotomy.