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Use of peritoneal dialysis for acute kidney injury during the COVID-19 pandemic in New York City: A multicenter observational study

Kidney International May 01, 2021

Chen W, Caplin N, El Shamy O, et al. - Researchers undertook this multicenter, retrospective, observational study to ascertain whether acute peritoneal dialysis (PD) is feasible for acute kidney injury during the coronavirus disease 2019 (COVID-19) pandemic. They included 94 patients who underwent acute PD in New York City in the Spring of 2020. Relative to the levels before kidney replacement therapy start, mean serum potassium reduced from 5.1 ± 0.9 to 4.5 ± 0.7 on PD Day 3 and 4.2 ± 0.6 mEq/L on Day 7; mean serum bicarbonate rose from 20 ± 4 to 21 ± 4 on PD Day 3 and 24 ± 4 mEq/L on Day 7. Post-median follow up of 30 days, deaths of 46% patients and renal recovery in 22% were documented. Factors identified as significant predictors of mortality included male gender and mechanical ventilation on admission. Overall, findings demonstrate the feasibility of rapid implementation of an acute PD program despite resource constraints and this intervention can save lives during crises such as the COVID-19 pandemic.

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