Use of gabapentin in posterior spinal fusion is associated with decreased postoperative pain and opioid use in children and adolescents
Journal of Spinal Disorders & Techniques Jun 06, 2019
Trzcinski S, et al. - In this retrospective cohort study of 129 children aged 10 to 21 years undergoing posterior spinal fusion (PSF) for adolescent idiopathic scoliosis, researchers examined how gabapentin use associates with inpatient postoperative daily pain scores and opioid use in these children. They defined adjuvant gabapentin exposure as at least 15 mg/kg/d by postoperative day 1 with an initial loading dose of 10 mg/kg on the day of surgery. Outcomes revealed improved pain scores and decreased opioid use in the first 48 to 72 hours postoperatively in correlation to adding gabapentin as adjuvant therapy for adolescent PSF, beginning on day of surgery.
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