Patberg E, Wells M, Vahanian S, et al. - Researchers conducted a prospective cohort study of pregnant women undergoing cervical length screening assessment via transvaginal ultrasound examination at 18 – 22 weeks gestation with the aim to create standard cervical elastography nomograms for singleton pregnancies at 18-22 weeks gestation using the E-cervix ultrasound application. In addition, they examined intra-observer reliability of the E-cervix elastography parameters as well as investigated the utility of these cervical elastography measurements in the prediction of spontaneous preterm birth. Five quantitative parameters (Internal Os Stiffness, External Os Stiffness, Internal to External Os Stiffness Ratio, Hardness Ratio, Elasticity Contrast Index) were calculated using a semi-automatic, cervical elastography application (E-cervix) during the transvaginal examination and a standard nomogram for each one of them was created. Per findings, the measures of cervical elastography parameters are reliable and remain stable across 18-22 weeks gestation. In a multivariable model adjusting for history of preterm birth, gravidity, ethnicity, cervical cerclage and vaginal progesterone use, they observed significant correlation of increasing Elasticity Contrast Index with an elevated risk of spontaneous preterm birth and hence Elasticity Contrast Index may be a useful parameter for future research.