Hoe V, Haller B, Yao HH, et al. - A systematic review was conducted to evaluate and compare the effectiveness and safety of all urethral bulking agents (UBAs) available for the treatment of stress urinary incontinence in women. Researchers carried out searches of the Ovid Medline, Embase, and PubMed databases. They screened a total of 583 articles and 56 articles were finally included. They conducted a qualitative analysis. The study demonstrates the use of Bulkamid and Macroplastique, which has shown short-term effectiveness of 30%–90% and 40%–85% respectively, and long-term efficacy of 42%–70%, and 21%–80%, respectively. Bulkamid seems to have a more favorable safety profile, with no cases of erosion or migration of products correlated with its use. As per the findings, direct comparisons of UBAs have not been conducted.