Wagner P, et al. - In a large population-based, single center cohort with 10,756 patients who underwent hysterectomy for benign indications between 2003 and 2016, researchers determined the incidence and features of unforeseen malignant pathologies of the uterine corpus. They confirmed 45/10,756 (0.42%) cases of unexpected malignancies of the uterine corpus (UUM) after chart and gynecopathological review. Cases with endometrial carcinomas (UEC) and uterine sarcomas (UUS) were 33/45 (73.3%) and 12/45 (26.7%), respectively. Also, they noted that, 27/33 (81.8%) UEC were FIGO IA, 5/33 (15.2%) FIGO IB and 1/33 (3%) FIGO stage II disease. Findings revealed that the diagnosis of UUM was rare (0.42%). Preoperative diagnosis was difficult due to majority of UUM being early stage. A generally favorable patient outcome was observed in case of UEC. When performing hysterectomy for a benign indication, all preoperative findings should be taken into consideration to make a careful choice regarding the appropriate surgical approach. The residual risk of UUM should always be discussed with patients.