Sawhney R, Ahsanuddin S, Sheorey L, et al. - Since giant cell sarcomas (GCS) are rare head and neck neoplasms, researchers sought to examine clinicopathologic and demographic features, analyze the treatment of choice, and identify prognostic factors of this malignancy. The Surveillance, Epidemiology, and End Results database was searched for all GCS patients diagnosed between 1973 and 2014. There were 440 cases of GCS of the head and neck identified. The average age at diagnosis was 74.4 years, with 86.8% of those diagnosed being white, 82.5% being male, 70.7% being insured, and 88.2% living in a metropolitan area. The most frequent primary site (42.5%) was connective tissue. GCS is most commonly seen in the connective tissue of the head and neck, with a high chance of survival. The only treatment option is surgery.