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Ultraprocessed food and chronic noncommunicable diseases: A systematic review and meta‐analysis of 43 observational studies

Obesity Reviews Feb 12, 2021

Lane MM, Davis JA, Beattie S, et al. - In this systematic review and meta‐analysis, researchers sought to explore the connection between consumption of ultraprocessed food and noncommunicable disease risk, morbidity and mortality. Forty‐three observational studies were involved (N = 891,723): 21 cross‐sectional, 19 prospective, two case‐control and one conducted both a prospective and cross‐sectional analysis. The meta-analysis showed consumption of ultraprocessed food was correlated with increased risk of overweight, obesity, abdominal obesity, all‐cause mortality, metabolic syndrome and depression in adults as well as wheezing but not asthma in adolescents. In addition, consumption of ultraprocessed foods in adults was associated with cardiometabolic diseases, frailty, irritable bowel syndrome, functional dyspepsia and cancer (breast and overall) while also being associated with adolescent metabolic syndrome and childhood dyslipidemia. Although links between the consumption of ultraprocessed food and certain intermediate risk factors in adults have also been highlighted, further studies are needed to define associations in children and adolescents more clearly.

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