Barb D, Repetto EM, Stokes ME, et al. - Diabetes mellitus (DM) had a modest impact on steatosis in this US cohort, which was predominantly caused by obesity. DM added a significant risk of fibrosis to people with overweight or obesity, implying that screening is essential in adults with DM.

• Candidates (National Health and Nutrition Examination Survey 2015-2016 database) involved 834 middle-aged individuals with DM (21.7%) and 3,007 without DM (78.3%).

• The prevalence of nonalcoholic fatty liver disease increased with BMI.

• Steatosis was higher in people with overweight with DM vs without DM and in people with obesity with DM vs without DM.

• Diabetes considerably raised the proportion of those who were at moderate-to-high risk of fibrosis.

• The risk nearly doubled in the group with a high risk of advanced fibrosis.

• DM raised the proportion of persons with a moderate or high risk of fibrosis by 1.8- and 2.5-fold, respectively, among those who were obese.