Schroeder M, et al. - Via involving a total of 6,142 treatment-naïve eyes at baseline, from the Swedish Macula Registry (SMR), researchers explored the risk factors for visual acuity (VA) below ≤ 35 letters of the Early Treatment Diabetic Retinopathy Study due to neovascular age-related macular degeneration (nAMD) during a two-year follow-up. According to results, 12.7% of eyes declined to a final VA of ≤ 35 letters in eyes treated for wet AMD and studied for 2 years. Visual acuity, worse-seeing eye treated, age and membrane size turned out as the baseline features that had significantly affected visual decline to ≤ 35 letters during the two-year follow-up.