Sato T, et al. - In this prospective, single-centre, three-arm randomized trial, researchers conducted a 12-month comparison between the different extents and locations of Schlemm’s canal incisions during suture trabeculotomy ab interno for open-angle glaucoma (OAG). In total, 99 eyes of 99 patients were randomly assigned to one of three groups: the 360° incision group (n = 34), the upper-180° incision group (n = 34), and the lower-180° incision group (n = 31). Intraocular pressure (IOP), number of medications, and complications have been assessed until 12 months after surgery. The mean IOP (±SD) in all eyes was decreased from 18.6 (5.9) mmHg with 3.1 (1.1) medications to 13.7 (3.4) mmHg (20.8% reduction) with 1.4 (1.3) medications at postoperative 12-month. Throughout 12 months of follow-up, each group produced similar mean reductions in both IOP and the number of medications. During suture trabeculotomy ab interno for OAG, the different extents and locations of Schlemm’s canal incisions, including the 360° incision, the upper-180° incision, and the lower-180° incision, do not modify both the IOP reduction and the medications throughout 12 months of follow-up.