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Triplex HRM assay for the simultaneous assessment of IL28B rs12979860, ABCB11 rs2287622, and RNF7 rs16851720 genotypes in chronic hepatitis C patients

Journal of Molecular Diagnostics Sep 08, 2017

Enache EL, et al. - This trial entailed the exploration of the efficacy of triplex HRM assay, in chronic hepatitis C (CHC) patients. This assay encompassed a diagnostic test for simultaneous genotyping of IL28B, ABCB11 and RNF7 in CHC patients. Reliable and inexpensive, the assay ought to yield beneficial information regarding the clinical management of CHC, like detection of patients at risk of rapid disease progression or with high chances of response to classical therapy.
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