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Treponema pallidum infection predicts sexually transmitted viral infections (hepatitis B virus, herpes simplex virus-2, and human immunodeficiency virus) among pregnant women from rural areas of Mwanza region, Tanzania

BMC Pregnancy and Childbirth Nov 09, 2019

Ng’wamkai G, Msigwa KV, Chengula D, et al. - Researchers examined pregnant women from three rural hospitals/clinics providing antenatal care in the Mwanza region, Tanzania for the prevalence of viral sexually transmitted infections (STIs) in this population. From February to May 2018, they screened a total of 499 pregnant women [median age: 25 (IQR: 22–31) years]. Of these, 78 women had at least one sexually transmitted viral infection. HIV, hepatitis B virus, hepatitis C virus, herpes simplex virus-2 (HSV-2) IgG and HSV-2 IgM were found to be prevalent in 25(5.0%), 29(5.8%), 2(0.4%), 188(37.7%) and 24 (4.8%), respectively. Findings revealed that among pregnant women in rural areas of the Mwanza region, a significant proportion has at least one sexually transmitted viral infection. This was independently predicted by positive T. pallidum serostatus. For reducing the viral STIs among these women, they recommend strengthening and expansion of ANC screening package to include screening of STIs. This may, in turn, reduce the associated morbidities and mortalities.
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