Salah HM, Minhas AMK, Khan MS, et al. - Analyzing trends in hospitalizations for heart failure (HF), acute myocardial infarction (AMI), and stroke in the United States (US), it was found that a progressive increase in hospitalizations for HF has happened since 2013, which is in contrast to the trend of AMI and stroke hospitalizations. Reduction in in-hospital mortality for HF, AMI, and stroke hospitalizations has been observed from 2004 to 2018.

• This is a retrospective study of the National Inpatient Sample weighted data from 2004 to 2018, including hospitalized adults ≥18 years with a primary discharge diagnosis of HF, AMI, or stroke.

• For HF, AMI, and stroke, there occurred 33.4 million hospitalizations, with most being for HF (48%).

• Following an initial fall in HF hospitalizations, a progressive increase in HF hospitalizations occurred between 2013 and 2018 (4.0/1000 US adults in 2014 to 4.9 hospitalizations/1,000 US adults in 2018).

• AMI hospitalization reduced (3.1 hospitalizations/1000 US adults in 2004 to 2.5 hospitalizations/1,000 US adults in 2010), and remained stable between 2010-2018.

• For stroke hospitalization, a small but significant increase was evident after 2011 that reached 2.5 hospitalizations/1,000 US adults in 2018.

• For HF, AMI, and stroke hospitalizations, reduction in adjusted length of stay and In-hospital mortality was observed.