Trends in fractures in patients with spondyloarthritis: A nationwide population-based study (TREND-EspA study)
Osteoporosis International Aug 05, 2021
Mazzucchelli R, Almodovar R, Dieguez-Costa E, et al. - The study found only an increase of axial fractures, more specifically vertebral fractures, in spondyloarthritis (SpA). In both cohorts, the trend in incidence is similar.
The age and gender-adjusted rates per 100,000 inhabitants/year of total fracture and different types of fracture were 45.72 any fractures, 17.64 axial, and 28.02 peripheral; 29.42 osteoporotic (12.67 vertebra, 12.29 hip, 1.50 pelvis, 1.82 humerus and 2.09 radius) in the SpA cohort.
There were 65.79 any, 12.08 axial, 51.52 peripheral; 31.17 osteoporotic (4.94 vertebra, 16.15 hip, 2.29 pelvis, 3.64 humerus, 5.38 radius) in the non-SpA cohort.
The trend in incidence rate for total fracture and different types of fracture increased similarly for both cohorts between 1999 and 2015.
An increase of axial fractures was found (AOR 1.444; 95%CI 1.297–1.609), and specifically of vertebral fractures (AOR 2.440; 95%CI 2.097–2.839) in the SpA cohort. It has been reported that other types of fractures did not increase.
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