Trends and outcomes associated with using long-acting opioids during delivery hospitalizations
Obstetrics and Gynecology Sep 28, 2018
Duffy CR, et al. - Researchers evaluated the tendencies in usage of long-acting opioids during delivery hospitalizations via analyzing the Perspective database (an administrative inpatient database that includes receipt of medication). Methadone, formulations including buprenorphine and extended-release formulations of oxycodone, morphine, fentanyl, and other opioids were evaluated in this study. Findings revealed increased use of methadone and buprenorphine, supporting the viability of using medications during pregnancy and uptake of clinical recommendations for women with opioid use disorder. Decreased maternal morbidity was correlated with the use of methadone and buprenorphine, although causation cannot be presumed from this study model.
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