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Treatment of contact lens related dry eye with antibacterial honey

Contact Lens and Anterior Eye Oct 14, 2017

Wong D, et al. - The goal of this analysis was to figure out the consequences of Manuka (Leptospermum sp.) honey eye drops (Optimel, Melcare, Australia) on dry eye in contact lens wearers. In addition, it investigated the safety of the honey eye drops in contact lens wear and contact lens wearers’ compliance. A reduction was noted in the symptoms of dry eye in contact lens wearers due to the Optimel eye drops. These drops were safe to use. Additional analysis was warranted with regard to a longer treatment period in order to examine the effect on clinical signs of dry eye.

Methods

  • The design of this research was a prospective, randomised, cross over study, examiner masked, pilot treatment trial.
  • The recruitment consisted of Twenty-four participants aged 20 to 55 years with contact lens related dry eye.
  • They were randomised to two treatment groups and 20 completed the study.
  • One group used Optimel eye drops twice a day for two weeks followed by conventional lubricant (Systane Ultra, Alcon) therapy for two weeks; the other group completed the treatments in the reverse order.
  • Prior to and following each treatment, an examination was performed of the dry eye symptomology, ocular surface inflammation, and tear quantity and quality.
  • A daily log detailing their usage of treatments and any issues was filled by the candidates.

Results

  • Marked improvement was noted in the dry eye symptoms after the Optimel treatment.
  • Patients with more severe symptoms at baseline illustrated a greater improvement in symptoms.
  • There were no prominent variations in the objective signs of dry eye.
  • This was possibly attributed to the short treatment duration.
  • Good adherence to Optimel treatment was exhibited by seventy-five% of contact lens wearers.
  • 95% of the individuals did not face any issues while using this product.

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