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Transient episodes of hemiparesis in Sturge Weber syndrome – causes, incidence and recovery

European Journal of Paediatric Neurology Dec 04, 2019

Tillmann RP, et al. - Given that children suffering from Sturge Weber Syndrome (SWS) present with seizures, acquired hemiparesis, transient hemiparesis and intellectual disabilities, researchers performed this retrospective cohort analysis to determine the incidence of transient episodes, their recovery time if full recovery was accomplished, and events related to the transient episode. This study included 102 children with a diagnosis of SWS, with a mean age of 10.86 years, who attended a tertiary multidisciplinary clinic from September 2013 to September 2016. Permanent hemiparesis was developed in 47/102 cases with SWS. Presentation with transient episodes was made by 32/102. Epilepsy developed in all children with transient hemiparesis. After a transient episode, 24 hours (range 1minute-4392 hours) was identified as the median recovery time to previous function. Within 6 months, full recovery from the transient episode was seen in all participants. Seizures or a blow to the head were identified as the factors related to transient episodes. These aspects of SWS were addressed in the largest cohort of children with SWS. Service development, including alteration in method to record details of transient episodes, was informed by these revelations.
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