Elbadawi A, et al. - Through the Nationwide Inpatient Sample Database (2012-2016), a propensity-score-matched analysis based on 25 clinical and hospital variables was performed by the researchers to compare subjects with rheumatoid arthritis (RA) who underwent surgical aortic valve replacement (SAVR) to those who underwent transcatheter aortic valve implantation (TAVI). A total of 5,640 hospitalizations with RA who underwent isolated AVR, out of whom 2,465 who underwent TAVI were recruited in this study. A rising trend in TAVI procedures during the study years was observed. A trend towards decreased in-hospital mortality in TAVI vs SAVR was noted, however, it did not reach statistical importance. TAVI was correlated with lower rates of postoperative bleeding, blood transfusion, AKI, cardiac tamponade and discharges to SNF. Moreover, TAVI was related to a greater rate of complete heart block and pacemaker implantations. In cardiogenic shock, acute stroke, acute myocardial infarction, and vascular complications, no variations among both groups was discovered. Hence, no significant variation in in-hospital mortality among TAVI and SAVR in subjects with RA was ascertained. Furthermore, TAVI was correlated with lower rates of AKI and bleeding complications at the expense of a greater incidence of pacemaker implantations.