Lovinsky-Desir S, Lussier SJ, Calatroni A, et al. - Since there is little understanding of trajectories of adiposity throughout early childhood in children at high-risk for developing asthma in urban United States cities, thus, researchers herein analyzed a longitudinal birth cohort of predominantly Black and Latinx children (n = 418) to define trajectories of adiposity in them employing various different repeated measures including body mass index (BMI) z-score, bio-impedance analysis (BIA), leptin and adiponectin in the first 10 years of life. They found three trajectories for BMI z-score, BIA, and leptin and 2 for adiponectin. Among children at high-risk for developing asthma, it was found that trajectories of adiposity were not related to asthma or lung function. The lack of a relationship could be explained by risk factors linked with geography, social and demographic factors that are unique to specific populations, and these risk factors should be taken into account in obesity and asthma studies.