Chang YJ, Bellettiere J, Godbole S, et al. - Given sedentary behavior is pervasive, particularly in older adults, and is related to cardiometabolic disease and death, and links between cardiometabolic biomarkers and sitting time are not investigated in older women, as are likely ethnic disparities, so, researchers determined ethnic disparities in sitting behavior and links with cardiometabolic risk among overweight/obese postmenopausal women (n = 518; mean ± SD age 63 ± 6 years; mean body mass index 31.4 ± 4.8 kg/m²). Hispanic women (n = 102) were compared with non-Hispanic women (n = 416) in terms of sitting, using multivariable linear regression. Relative to non-Hispanic women, Hispanic women sat, on average, 50.3 minutes less/day and were found to have a shorter (3.6 minutes less) mean sitting bout duration. Deleterious link of longer total sitting time with fasting insulin and triglyceride levels, insulin resistance, body mass index and waist circumference, was identified among all women; longer mean sitting bout duration was found to be deleteriously related to fasting glucose and insulin levels, insulin resistance, body mass index and waist circumference. Among overweight/obese older women, findings revealed ethnic variations in 2 objectively assessed parameters of sitting behavior, as well as detrimental links between parameters and cardiometabolic biomarkers. Compared with non-Hispanic women, Hispanic women may display a greater detrimental link between mean sitting bout duration and fasting glucose.