Samimi M, Le Gouge A, Boralevi F, et al. - Researchers conducted this randomized, double‐blind, controlled study to compare the safety and effectiveness of topical rapamycin and betamethasone dipropionate ointment for oral erosive lichen planus (OELP). Study participants were randomized to receive treatment with betamethasone dipropionate ointment 0.05% in Orabase® or topical rapamycin solution (1 mg/mL) on lesions twice daily for 3 months, followed by 3 months of observation. Seventy-six patients were randomized and 75 received treatment (rapamycin, n = 39; betamethasone, n = 36) during a 4‐year period. In 43.6% of patients with rapamycin (mostly burning sensation, impaired taste) and 27.8% with betamethasone (mostly oral candidiasis), adverse events occurred. The authors found no superiority of topical rapamycin over betamethasone dipropionate ointment for OELP although the research was limited by inadequate recruitment. It seems that superpotent topical corticosteroids will remain the first‐line treatment for OELP given the rapid remission and pain relief in the betamethasone group.