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Thyroid function screening in children and adolescents with mood and anxiety disorders

The Journal of Clinical Psychiatry Aug 09, 2019

Luft MJ, Aldrich SL, Poweleit E, et al. -In psychiatrically hospitalized children and adolescents (3–19 years) with mood/anxiety disorders (DSM-IV and DSM-5 criteria), researchers examined the prevalence of abnormal thyroid-stimulating hormone (TSH) measures. In addition, they sought clinical and demographic factors that are predictive of abnormal TSH measures. Approximately 6% of participants (N = 1,017, mean ± SD age = 14.7 ± 2.24 years) had abnormal TSH concentrations; < 1% of the total sample presented with thyroid disease. As per findings, patients with recent weight gain, those treated with benzodiazepines, and girls with a history of abnormal uterine bleeding/menometrorrhagia should be the focus of targeted screening. Patients with thyroid disease vs those with elevated TSH and normal active thyroid hormone concentrations were older but did not differ in sex distribution.

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