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Thrombocytopenia and clinical outcomes in intracerebral hemorrhage: A retrospective multicenter cohort atudy

Stroke Jan 17, 2021

Mrochen A, Sprügel MI, Gerner ST, et al. - In patients with intracerebral hemorrhage (ICH) with or without prior antiplatelet therapy (APT), the effect of thrombocytopenia on hematoma enlargement (HE), functional outcome, and mortality was explored. In the analysis, 11.4% (52 of 458) of those under APT and 14.0% (242 of 1725) without APT presented with thrombocytopenia on admission out of an overall 2,252 patients with ICH. The findings revealed that among ICH patients, thrombocytopenia does not influence rates of HE and functional outcome, neither in patients with nor without APT. Due to increased mortality, for ICH patients, the significance of platelet transfusions with thrombocytopenia and previous APT should be evaluated in future trials.

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