Three-year longitudinal motor function and disability level of acute flaccid myelitis
Pediatric Neurology Dec 07, 2020
Chong PF, Kira R, Torisu H, et al. - In a cluster of pediatric patients with acute flaccid myelitis (AFM) associated with the enterovirus D68 (EV-D68) outbreak in 2015, researchers sought to describe the long-term motor outcome and disability level. At the acute (nadir), recovery (6 months) and chronic (3 years) stages, clinical data, including the motor function (manual muscle strength test) and other neurological symptoms, were gathered for this nationwide follow-up questionnaire analysis study. Clinical data were available for 33 AFM patients (13 females, 20 males; median age = 4.1 years). Among patients with tetraplegia or triplegia, paraplegia, and monoplegia at the acute stage, 2/7, 4/13, and 2/13 showed complete recovery without paralysis, out of those 5/7, 8/13, and 2/13 who noted improvement with lesser limb involvement at the chronic stage, respectively. AFM has a high rate of persistent motor deficits of 1–2 limb paralysis. However, disability level of patients with AFM usually improved at 3 years.
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