Reumueller A, Wassermann L, Salas M, et al. - In the present study, the researchers sought to evaluate the signal composition of cone photoreceptors three-dimensionally in healthy retinas utilizing adaptive optics optical coherence tomography (AO-OCT). The sample consisted of ten individuals (20 healthy eyes), aged 23 to 67 years. Eyes were examined using AO-OCT after routine ophthalmological assessments. Qualitative and quantitative changes in cone signals are found not only in various eccentricities and meridians, but also in various photoreceptor layers in healthy individuals. When determining the integrity of cone photoreceptors in healthy and diseased eyes using adaptive optics technology, the difference between cone planes has to be noted.