Iwata T, Machida H, Matsuo K, et al. - Via performing a retrospective cohort of women ages < 45 years with clinical stage I–II cervical cancer (n = 393), researchers sought to determine the timing and a prediction model for pregnancy in early-stage cervical cancer patients who underwent fertility-sparing trachelectomy. Subsequent pregnancies were reported in 77 (21.6%) women after fertility-sparing trachelectomy with 1-, 2-, and 5-year cumulative pregnancy rates of 2.8%, 6.2%, and 17.4%, respectively. Multivariable analysis revealed the following factors to be independently linked with an increased chance of developing a subsequent pregnancy: younger age, being married, and postoperative reproductive treatment. They proposed the subsequent pregnancy index (SPI) score to predict the likelihood of having pregnancy; it can be calculated based on age, marital status, and reproductive treatment (2, 2, and 4 points, respectively). This score is identified as valuable for predicting subsequent pregnancy in women with early-stage cervical cancer undergoing fertility-sparing trachelectomy.