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The sustained therapeutic effects of percutaneous posterior tibial nerve stimulation in the treatment of neurogenic lower urinary tract symptoms in patients with Parkinson disease: 24-months clinical and urodynamic results

Urology Feb 10, 2021

Kabay S, Kabay SC., et al. - In Parkinson disease (PD) patients with detrusor activity (DA), researchers conducted this study to determine the sustained therapeutic impact of percutaneous posterior tibial nerve stimulation (PTNS) treatment over 24 months. The study enrolled 76 patients (44 men and 32 women). After 12 weeks of therapy, PTNS was applied at intervals of 14 days over 3 months, at intervals of 21 days over 3 months, and at intervals of 28 days over 24 months. The discrepancies between the comparative parameters at baseline and at the end of 24 months were as follows; daytime incidence declined by 4.6 voids per day, urge incontinence reduced by 4.2 episodes per day, urgency episodes were reduced by 6.2 episodes per day, nocturia was reduced by 2.4 voids and voided volume improved by a mean of 71.4 cc. Such findings showed substantial changes in both voiding and urodynamic parameters under PTNS treatment with a tapering protocol for during 24-months in PD with DA.

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