Meisel P, et al. - Since women are generally periodontally healthier than man but they show higher systemic levels of inflammatory markers, researchers ascertained if this paradox can be explained by different ramifications of adiposity or body shape. Anthropometric and periodontal parameters, C-reactive protein (CRP) and fibrinogen as markers of inflammation were determined in 3,268 patients from the Study of Health in Pomerania. The opposite sex role of periodontitis and obesity on CRP levels was confirmed after adjusting for age, waist-hip ratio (WHR), glycated hemoglobin, smoking, education and grip strength. In both men and women, WHR and BMI were linked to CRP. According to findings, concentrations of systemic CRP are affected in men by periodontitis and obesity. Adiposity in women is more significant than in men that override the impact of periodontal measures. In women, but not in men, HbA1c significantly contributed to PD.