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The sex discrepancy effects of fruit and vegetable intake on pancreatic cancer risk; a large Korean cancer screening cohort study

Digestive and Liver Diseases Aug 26, 2021

Nam SY, Jo J, Lee WK, et al. - Women and men who consumed high amounts of dietary vegetables and fruit, respectively, were found to have reduced risk of development of pancreatic cancer.

  • This study involved 3,605,959 individuals (44% men) without cancer at baseline.

  • Vegetable and fruit intakes were measured.

  • 9-year follow-up revealed occurrence of pancreatic cancer in 10,469 persons (5,384 men).

  • In adjusted analyses, reduction in pancreatic cancer was achieved with daily intake of more than five vegetable types vs no vegetable intake [adjusted hazard ratio (aHR) = 0.82].

  • Vegetable consumption markedly decreased pancreatic cancer in females (aHR = 0.84 for 1–2 vegetable types, 0.84 for 3–4 and 0.69 for ≥ 5), but no impacts were seen in males.

  • Consumption of fruits decreased pancreatic cancer in men (aHR = 0.87 for 3–4 servings/week, and 0.84 for ≥ 7), but no impacts were seen in women.

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