Tringale KR, et al. - Using data from the US National Health and Nutrition Examination Survey, researchers focused on a 10-year time period assessing self-reported marijuana and prescription opioid use among people with cancer. Of 19,604 respondents (aged 20 to 60 years), 826 people with cancer were matched to 1,652 controls. A considerable proportion of respondents with cancer (40.3%) self-reported marijuana use; a significantly higher prevalence of opioid use was also evident. In a multivariable conditional logistic regression, current opioid use, but not current marijuana use, was associated with cancer. Odds of marijuana use significantly increased over time, whereas the odds of opioid use did not significantly change among all survey respondents. Although they found no significant alteration in the opioid use from 2005 until 2014 among all respondents, an increase in marijuana use was reported, possibly indicating increased availability and legislative changes. No significant impact of a cancer diagnosis on longitudinal opioid or marijuana use was evident.