The role of blood pressure in risk of ischemic and hemorrhagic stroke in type 1 diabetes
Cardiovascular Diabetology Jul 17, 2019
Hägg-Holmberg S, et al. - Among participants (n=4,105) from the nationwide Finnish Diabetic Nephropathy Study who had type 1 diabetes without stroke at baseline, researchers examined the link between different blood pressure variables and the risk of stroke, focusing on the potential nonlinearity of this link. The mean age at baseline and median duration of diabetes were 37.4 ± 11.9 years and 20.9 years, respectively. In the study sample, 52% were men. In individuals with type 1 diabetes, findings revealed independent associations of different blood pressure variables with an increased risk of stroke. The risk of ischemic stroke was increased by systolic blood pressure (SBP), pulse pressure, and mean arterial pressure (MAP), while the risk of hemorrhagic stroke was increased by SBP, diastolic blood pressure, and MAP. At blood pressure levels less than the current suggested treatment guidelines, a linear increase in the risk of stroke, ischemic stroke, and hemorrhagic stroke was shown.
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