Mendes FAR, et al. - Researchers examined patients with moderate or severe asthma to assess if the %HRR–%VO₂R link and %HRR–VO_2peak link are influenced in these patients. They also investigated the impact of airway obstruction and aerobic capacity on these links. For 93 asthmatics, they calculated a linear regression using the paired %VO₂R–%HRR and %VO_2peak–%HRR. They also calculated mean slope and y-intercept and compared these with the line of identity (y-intercept = 0, slope = 1). This was done for all patients and subgroups for low and normal VO_2peak and low and normal FEV₁. For the first time ever, a constant equivalence between %HRR and %VO₂R in outpatients with moderate or severe asthma was confirmed in this study. The unreliability of the link between %HRR and %VO_2peak was also suggested. Independently of the pulmonary function and fitness level, use of %HRR in relation to %VO₂R is supported for the estimation of exercise intensity in these patients.