Jiang M, Fares AF, Shepshelovich D, et al. - Researchers examined the effect of sex, smoking and race on the association between body-mass-index (BMI) and overall survival (OS) in non-small-cell-lung-cancer (NSCLC). They pooled data from 16 individual ILCCO (International Lung Cancer Consortium) studies, including 20,937 NSCLC patients with BMI values (females = 47%; never-smokers = 14%; White-patients = 76%). Findings revealed worse outcomes in correlation with being underweight and obese female ever-smokers among White patients. These BMI links were absent in Asian-patients and never-smokers. In the extremes of BMI, more favorable results were evident in Black-patients vs White-patients. The factors that may account for disparities in these BMI-OS links include body composition in Black-patients, and NSCLC subtypes more frequently observed in Asian-patients, and never-smokers.