Atchison EA, et al. - Researchers pursued an investigation of the sustained variations in intraocular pressure (IOP) after intravitreous injections of anti-vascular endothelial growth factor (VEGF) drugs in patients seeing an ophthalmic provider. Herein, anti-VEGF intravitreous injections correlated with a minor, yet, statistically marked decrease in IOP over time. A sustained clinically prominent IOP rise was experienced by an average 2.6% patients with these drugs compared to 1.5% in the fellow untreated eyes. Such a rise was not noted with aflibercept.