Mandelbaum RS, Adams CL, Yoshihara K, et al. - In view of mounting evidence for the role of the distal fallopian tubes in the pathogenesis of epithelial ovarian cancer, opportunistic salpingectomy at the time of benign gynecologic surgery has increased. Researchers here aimed at ascertaining trends in opportunistic salpingectomy in women undergoing benign hysterectomy and investigating the possible contribution of the publication of the tubal hypothesis in 2010 to these trends. In this population-based retrospective observational study, the National Inpatient Sample between January 2001 and September 2015 was assessed for women < 50 years of age who underwent inpatient hysterectomy for benign gynecologic disease. They identified 98,061 (9.0%) women who underwent hysterectomy with opportunistic salpingectomy and 997,237 (91.0%) women who had hysterectomy alone without opportunistic salpingectomy.  A gradual increase in the performance of opportunistic salpingectomy was observed from 2.4% to 5.7% between 2001-2010 (2.4-fold increase), predicting a 7.0% rate of opportunistic salpingectomy in 2015. However, in 2010, there began a substantial increase in the rate of opportunistic salpingectomy and reached 58.4% by 2015 (10.2-fold increase). Findings suggest that in the United States, clinicians rapidly adopted opportunistic salpingectomy at the time of benign hysterectomy following the publication of data implicating the distal fallopian tubes in ovarian cancer pathogenesis in 2010. By 2015, opportunistic salpingectomy at benign hysterectomy had been performed in nearly 60% of women.