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The pathology of lumbosacral lipomas: Macroscopic and microscopic disparity have implications for embryogenesis and mode of clinical deterioration

Histopathology May 02, 2018

Jones V, et al. - Experts sought to investigate if the spinal cord dysfunction reflected a primary developmental dysplasia or whether it occurred secondarily to mechanical traction (spinal cord tethering) with growth in patients who had undergone surgical resection of lumbosacral lipomas (LSL). Findings shed light on the heterogeneity of tissue types within all samples, not reflected in the nomenclature. It was determined that the diversity of tissue types, consistent across all subtypes, challenged the present notions regarding the embryogenesis of LSLs and the assumption that clinical deterioration was due to tethering.
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