Carney C, et al. - Using data from the Nurse Health Assessment, researchers investigated the moderating impact of disadvantaged childhood socio-economic position (SEP) on the associations of smoking, physical activity, obesity, occupational exposures, environmental tobacco smoke, and air pollution with lung function. Overall, 16,339 English residents, including women aged at least 20 years and men aged 25 years, were included. Findings revealed the associations of SEP, smoking, physical activity, obesity, occupational exposures, and air pollution with lung function. A significantly stronger negative link between disadvantaged childhood SEP and current smoking as well as with previously smoking and occupational exposures was indicated by interaction terms. According to the findings, a greater susceptibility of lung function to the negative impact of smoking and occupational exposures in adulthood may be seen in relation to disadvantaged SEP in childhood.