Hulens M, et al. - Via performing this review, researchers compared literature data regarding the characteristics of idiopathic intracranial hypertension (IICH), fibromyalgia (FM), and chronic fatigue syndrome (CFS). Further, they linked the shared data to an apparent underlying physiopathology, that is, increased intracranial pressure (ICP). Headaches, fatigue, cognitive impairment, loss of gray matter, involvement of cranial nerves, and overload of the lymphatic olfactory pathway were the characteristics which are shared by IICH, FM, and CFS. Increased ICP may be the causative factors explaining these shared characteristics. The pressure increase in the spinal canal and in peripheral nerve root sheaths induces widespread pain, weakness in the arms and legs, walking difficulties (ataxia), and bladder, bowel, and sphincter symptoms. Additionally, sympathetic overactivity symptoms and obesity were evident in frequent association with IICH, FM, and CFS. Particularly females showed a high prevalence of these conditions. Ehlers-Danlos syndrome is frequently noted in association with these conditions.