Schepis TS, et al. - This study was intended to distinguish latent classes of adults 50 years and older by past-year substance use, past-month substance use, and past-year substance use disorder diagnosis. Researchers performed a National Survey on Drug Use and Health is an annual nationwide cross-sectional U.S. survey including 35,229 civilians, non-institutionalized U.S. residents, 50 years and older. The results demonstrate that most adults 50 and older have lower risk profiles, but those engaged in prescription drug misuse or cocaine use are heavily substance-involved and need screening and likely multi-disciplinary intervention.